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Albion Baucom

structural biology specialist

Research

My research focuses on developing methods in 3D tomographic EM reconstructions. In particular I am interested in how to combine information from several different sources with tomographic reconstructions to solve symmetrical biological structures in 3D.

In addition to computational methods I also collaborate with lab members to help solve biological structures imaged by cryo and negative stain EM.

Before joining the Agard lab, I was a member of Dr. Harry Noller's lab at UC Santa Cruz. My research at UCSC focused on solving the x-ray structure of ribosomes isolated from the organism Thermus thermophilus. I also contributed to research efforts in the lab that included FRET studies, and methods in low resolution x-ray structure determination.

Outside of work my interests include, among other things, motorcycles, old trucks, and surfing.
Publications

Publications

Hickerson, Robyn, Majumdar, Zigurts K., Baucom, Albion E., Clegg, Robert M., Noller, Harry F., Measurement of Internal Movements within the 30S Ribosomal Subunit Using Forster Resonance Energy Transfer, Journal of Molecular Biology, Journal of Molecular Biology, 354(2):459-72, 2005

Noller, Harry F, Baucom, Albion E., Structure of the 70S Ribosome: Implications for Movement, Biochem Soc Trans 2002 30(6):1159-61.

Noller, Harry F., Yusupov, Marat M., Yusupova, Gulnara Z., Baucom, A. E., Cate, JHD, Translocation of tRNA during protein synthesis, FEBS Letters, 514(1):11-6, 2002.

Noller, H.F., Yusupov, M., Yusupova, G., Baucom, A. E., Lieberman, K., Lancaster, L., Dallas, A., Fredrick, K., Earnest, T.N., and Cate, J.H.D. Structure of the Ribosome at 5.5 Å Resolution and Its Interactions with Functional Ligands. Cold Spring Harbor Symposia on Quantitative Biology: The Ribosome, Volume 66. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York, pp. 57-66, 2001.

Yusupov, M. M., Yusupova, G. Zh., Baucom, A. E., Lieberman, K., Earnest T. N., Cate J. H. D., Noller, H. F., Crystal Structure of the Ribosome at 5.5 A Resolution, Science 292(5518):883-896, 2001.

Stawiski, E. W., Baucom, A. E., Lohr, S. C., Gregoret, L. M., Predicting Protein Function from Structure: Unique Structural Features of Proteases, Proceedings of the National Academy of Sciences of the United States of America 97(8):3954-8, 2000.

Bentz, J., Baucom, A. E., Hansen, M., Gregoret, L. M., Dinamo: Interactive Protein Alignment and Model Building., Bioinformatics (15):309-316., 1999.

Hansen, M, Baucom, A. E., Bentz, J., Gregoret, L. M., Dinamo: A Coupled Sequence Alignment Editor/Molecular Graphics Tool for Interactive Homology Modeling of Proteins., Pacific Symposium on Biocomputing 106-17, 1998.

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