Jeanne Stuckey replied: "Slider_lego has been a great tool for determining which side_chains would have reasonable fit into the density. Slider_guess worked well for me when I was trying to decide on the sequence for several long stretches of chain. (By long stretches, I mean 12 to 20 residue chains.) There are too many reasonable sequence fits in some proteins for 5 to 8 residue patches."