Current projects focus on ion channels, transporters, and combating antibodies in autoimmune disease. Transporters include those involved in drug resistance, and in packaging neurotransmitters.  Infectious disease focus areas include malaria, mycobacterium tuberculosis and HIV.

Focused on Identifying Protein Structures



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Structure Gallery

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  • Stroud LectureWiggle Wiggle Not a Trickle; Structure Specificity and Integrity at Biological Membranes
    Presented by Dr. Robert Stroud

    March 8, 2018 | 3:30 pm | Byers Auditorium

    Contact: Kenneth Laslavic, 415/476.8827

    UCSF Academic Senate's 61st Annual Faculty Research Lecture – Basic Science Awarded to Robert Stroud, PhD

    The Academic Senate is pleased to announce the selection of Robert Stroud, PhD, as recipient of the 61st Annual Faculty Research Lectureship – Basic Science for his prolific research on modern structural biology. The lecture, titled "Wiggle Wiggle Not a Trickle; Structure Specificity and Integrity at Biological Membranes", will take place on Thursday, March 8, 2018, at 3:30 p.m. in Byers Auditorium, Mission Bay Campus. The event will be simulcast and a reception will follow.

    A world leader in structural biology, Dr. Stroud's research has addressed a breadth of systems that impact a wide array of biological processes. This work has aimed to understand the molecular level cellular signaling and communication across cell membranes, and the macromolecular encoding of specificity and affinity at protein/protein and protein/ligand interfaces.

    Dr. Stroud has more than 340 peer reviewed publications and 300 structures to his credit.

    Dr. Stroud's contributions have been recognized by his election to the Royal Society of Medicine, the National Academy of Sciences, and the American Academy of Arts & Sciences

    Dr. Stroud is Professor of Biochemistry and Biophysics and Professor of pharmaceutical Chemistry in the Department of Department of Biochemistry and Biophysics. He received his PhD from University of London and completed postdoctoral training at California Institute of Technology. Dr. Stroud joined UCSF in 1976 to start the University's first structural biology program.

    The 61st Annual Faculty Research Lecture – Basic Science will be held in Byers Auditorium, Mission Bay Campus, on Thursday, March 8, 2018, at 3:30 p.m., and will be available to stream via simulcast. Refreshments will be provided. The lecture is open to the campus community and the general public.

    *** Since 1957, this award has been bestowed on an individual member of the UCSF faculty who has made a distinguished record in basic science. Nominations are made by UCSF faculty, who consider scientific research contributions of their colleagues and submit nominations for this prestigious award to the Academic Senate Committee on Research. Each year, the Committee on Research selects the recipient of this award.

    A list of the past recipients of the award can be viewed at

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  • Kapoor K, Finer-Moore J, Pedersen BP, Waight, Caboni L, Hillig R, Bringmann P, Heisler I, Mülle T, Siebeneicher H, Stroud RM (2016) Crystal structures of human GLUT1 bound to Cytochalasin B and novel inhibitors. Proc Natl Acad Sci USA. online Apr 12 2016 DOI 10.1073/ pnas.1603735113

    Kintzer A, Stroud RM (2016) Structure, inhibition and regulation of two-pore channel TPC1 from Arabidopsis thaliana. Nature. 531: 258-62 See also SSRL news update; ALS news and update

    Finer-Moore JS, Czudnochowski N, O'Connell JD IIIrd, Wang AL, Stroud RM (2015) Crystal Structure of the Human tRNA m(1)A58 Methyltransferase-tRNA3(Lys) Complex: Refolding of Substrate tRNA Allows Access to the Methylation Target. J Mol Biol 427: 3862-3876

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