Current projects focus on ion channels, transporters, and combating antibodies in autoimmune disease. Transporters include those involved in drug resistance, and in packaging neurotransmitters. Infectious disease focus areas include malaria, mycobacterium tuberculosis and HIV.
Wiggle Wiggle Not a Trickle; Structure Specificity and Integrity at Biological Membranes
Presented by Dr. Robert Stroud
March 8, 2018 | 3:30 pm | Byers Auditorium
NEWS FROM THE ACADEMIC SENATE
Contact: Kenneth Laslavic, 415/476.8827
UCSF Academic Senate's 61st Annual Faculty Research Lecture – Basic Science Awarded to Robert Stroud, PhD
The Academic Senate is pleased to announce the selection of Robert Stroud, PhD, as recipient of the 61st Annual Faculty Research Lectureship – Basic Science for his prolific research on modern structural biology. The lecture, titled "Wiggle Wiggle Not a Trickle; Structure Specificity and Integrity at Biological Membranes", will take place on Thursday, March 8, 2018, at 3:30 p.m. in Byers Auditorium, Mission Bay Campus. The event will be simulcast and a reception will follow.
A world leader in structural biology, Dr. Stroud's research has addressed a breadth of systems that impact a wide array of biological processes. This work has aimed to understand the molecular level cellular signaling and communication across cell membranes, and the macromolecular encoding of specificity and affinity at protein/protein and protein/ligand interfaces.
Dr. Stroud has more than 340 peer reviewed publications and 300 structures to his credit.
Dr. Stroud's contributions have been recognized by his election to the Royal Society of Medicine, the National Academy of Sciences, and the American Academy of Arts & Sciences
Dr. Stroud is Professor of Biochemistry and Biophysics and Professor of pharmaceutical Chemistry in the Department of Department of Biochemistry and Biophysics. He received his PhD from University of London and completed postdoctoral training at California Institute of Technology. Dr. Stroud joined UCSF in 1976 to start the University's first structural biology program.
The 61st Annual Faculty Research Lecture – Basic Science will be held in Byers Auditorium, Mission Bay Campus, on Thursday, March 8, 2018, at 3:30 p.m., and will be available to stream via simulcast. Refreshments will be provided. The lecture is open to the campus community and the general public.
*** Since 1957, this award has been bestowed on an individual member of the UCSF faculty who has made a distinguished record in basic science. Nominations are made by UCSF faculty, who consider scientific research contributions of their colleagues and submit nominations for this prestigious award to the Academic Senate Committee on Research. Each year, the Committee on Research selects the recipient of this award.
A list of the past recipients of the award can be viewed at http://tiny.ucsf.edu/QzEFLb.
Kintzer AF, Green EM,Dominik PK, Bridges M,Armache J-P,Deneka D, Kim SS, Hubbell W, Kossiakoff, AA, Cheng Y, Stroud RM. (2018) The structural basis for activation of voltage sensor domains in an ion channel TPC1. https://www.biorxiv.org/content/early/2018/07/21/373860 & Proc Natl Acad Sci U S A. –in press.
Kumar H, Finer-Moore JS,Jiang X,Smirnova I,Kasho V,Pardon E,Steyaert J, Kaback HR, Stroud RM. (2018) Crystal Structure of a ligand bound LacY/Nanobody Complex. Proc Natl Acad Sci U S A. –in press.
Finer-Moore JS. Lee TT, Stroud RM. (2018) A Single Mutation Traps a Half-Sites Reactive Enzyme in Midstream, Explaining Asymmetry in Hydride Transfer. Biochemistry 57: 2786-2795