2004–Current

2007

How U38, 39, and 40 of many tRNAs become the targets for pseudouridylation by TruA. Mol Cell 26: 189-203. Hur, S., Stroud, R.M. (2007).

TARP auxiliary subunits switch AMPA receptor antagonists into partial agonists. Science 318: 815-817. Menuz, K., Stroud, R.M., Nicoll, R.A., Hays, F.A. (2007).

The crystal structure of E. coli rRNA pseudouridine synthase RluE. J Mol Biol 367: 1459-1470252. Pan, H., Ho, J.D., Stroud, R.M., Finer-Moore, J. (2007).

X-ray structures of the signal recognition particle receptor reveal targeting cycle intermediates. PLoS ONE 2: e607. Reyes, C.L., Rutenber, E., Walter, P., Stroud, R.M. (2007).

Cell-free complements in vivo expression of the E. coli membrane proteome. Protein Sci 16: 966-976. Savage, D.F., Anderson, C.L., Robles-Colmenares, Y., Newby, Z.E., Stroud, R.M. (2007).

Structural basis of aquaporin inhibition by mercury. J Mol Biol 368: 607-617. Savage, D.F., Stroud, R.M. (2007).

Transmembrane transporters: an open and closed case. Proc Natl Acad Sci U S A 104: 1445-1446.Stroud, R.M. (2007).

Inhibitory complex of the transmembrane ammonia channel, AmtB, and the cytosolic regulatory protein, GlnK, at 1.96Å. Franz Gruswitz, Joseph O'Connell, III, and Robert M. Stroud. (2007) PNAS 104; 42-47.
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2006

The Amt/MEP/Rh family: structure of AmtB and the mechanism of ammonia gas conduction. Khademi, S., and Stroud, R.M. (2006) Physiology (Bethesda)21: 419-429.

Gas Channels for Ammonia. Khademi, S., and Stroud,R.M. (2006), Invited Chapter in Royal Society of Chemistry: Structural Biology of Membrane Proteins, ed., Reinhard Grisshammer and Susan K. Buchanan. Chapter 12, 212-234.

Aquaporins: Integral Membrane Channel Proteins. Stroud, R.M., Harries, W.E.C., Lee, J, Khademi, S., and Savage, D (2006), Invited Chapter  in Royal Society of Chemistry: Structural Biology of Membrane Proteins, ed., Reinhard Grisshammer and Susan K. Buchanan. Chapter 11, 195-211.

The Role of Protein Dynamics in Thymidylate Synthase Catalysis: Variants of Conserved 2'-Deoxyuridine 5'-Monophosphate (dUMP)-Binding Tyr-261. Zachary Newby, Tom T. Lee, Richard J. Morse, Yaoquan Liu, Lu Liu, Prasanna Venkatraman, Daniel V. Santi, Janet S. Finer-Moore, and Robert M. Stroud. (2006) Biochemistry Vol 45, 24.
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Substrate Recognition by RNA 5-Methyluridine Methyltransferases and Pseudouridine Synthases: A Structural Perspective. Sun Hur, Robert M. Stroud, and Janet Finer-Moore. (2006) The Journal of Biological Chemistry Vol. 281, No. 51, pp. 38969–38973.
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The Structure of a Ketoreductase Determines the Organization of the b-Carbon Processing Enzymes of Modular Polyketide Synthases. Adrian T. Keatinge-Clay, and Robert M. Stroud. (2006) Structure 14, 737–748.
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2005

Structural Basis for Conductance by the Archaeal Aquaporin AqpM at 1.68Å. Lee, J.K., Stroud, R.M.  (2005) Proc. Nat Acad Sci U S A 102, 18932-7.

On the Mechanism of Sensing Unfolded Protein in the Endoplasmic Reticulum.Credle, J.J., Finer-Moore, J.S., Papa, F.R., Stroud, R.M. and Walter, P. (2005) Proc Nat Acad Sci  102, 18773-18784

A unique RNA fold in the rumA-RNA-cofactor ternary complex contributes to substrate selectivity and enzymatic function. Lee, T., Agarwalla, S., Stroud, R.M. (2005) Cell 120, 599-611.
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Targeting proteins to membranes: structure of the signal recognition particle. Egea, P.F., Stroud, R.M., Walter, P. (2005) Current Opinion in Structural Biology 15:213-220.
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2004

De novo design of an IL-4 antagonist and its structure at 1.9Å. LaPorte, S.L., Forsyth, C.M., Cunningham, B.C., Miercke, L.J., Akhaven, D., Stroud, R.M. (2004) PNAS vol 102 no.6 1889-1894.
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Mechanism of association and reciprocal activation of two GTPases.
Shan, S. O., Stroud, R. M., Walter, P. (2004) PLoS Biol 2, e320
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An antibiotic factory caught in action.
Keatinge-Clay, A. T., Maltby, D. A., Medzihradszky, K. F., Khosla, C., Stroud, R. M. (2004) Nat Struct Mol Biol 11, 888-893.
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Mechanism of Ammonia Transport by Amt/MEP/Rh: Structure of AmtB at 1.35Å.
Khademi, S., O'Connell III, J., Remis, J., Robles-Colmenares, Y., Miercke L.J.W., Stroud, R.M. (2004) Science 305, 1587-1594. (Cover Article with Perspective by Knepper and Agre, 1573-1574)
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The Channel Architecture of Aquaporin 0 At 2.2 Å Resolution.
Harries, W.E.C., Akhavan, D., Miercke, L.J.W., Khademi, S., Stroud, R.M. (2004) Proc Nat Acad Sci 101, 14045-14050.
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Unraveling the interface of signal recognition particle and its receptor using chemical cross-linking and tandem mass spectrometry.
Chu, F., Shan, S.O. Moustakas, D.T., Alber, F., Egea, P.F., Stroud, R.M., Walter, P. Alma L. Burlingame, A.L. (2004) Proc. Nat Acad Sci 101, 16454-9
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Water and glycerol permeation through the glycerol channel GlpF and the aquaporin family.
Lee J.K., Khademi S., Harries W., Savage D., Miercke L., Stroud R.M. (2004). J Synchrotron Radiat 11, 86.

Mechanistic diversity of cytokine receptor signaling across cell membranes. Stroud R.M., Wells J.A. (2004). Science STKE 2004, re7.
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Substrate twinning activates the signal recognition particle and its receptor. Egea, P.F., Shan, S.O., Napetschnig, J., Savage, D.F., Walter, P., and Stroud, R.M. (2004) Nature 426 215-221.
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Redox reactions of the iron-sulfur cluster in a ribosomal RNA methyltransferase, RumA: optical and EPR studies. Agarwalla, S., Stroud, RM., Gaffney B.J. (2004). J Biol Chem 279, 34123-34129.
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