Signal Recognition Particle

Targeting proteins to membranes: structure of the signal recognition particle.
Egea, P.F., Stroud, R.M., Walter, P. (2005)
Current Opinion in Structural Biology 15:213-220.
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Mechanism of association and reciprocal activation of two GTPases.
Shan, S. O., Stroud, R. M., Walter, P. (2004)
PLoS Biol 2, e320
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Substrate twinning activates the signal recognition particle and its receptor.
Egea, P.F., Shan, S.O., Napetschnig, J., Savage, D.F., Walter, P., and Stroud, R.M. (2004)
Nature 426 215-221.
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Mechanistic diversity of cytokine receptor signaling across cell membranes.
Stroud R.M., Wells J.A. (2004).
Science STKE 2004, re7.
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Unraveling the interface of signal recognition particle and its receptor using chemical cross-linking and mass spectrometry.
Chu, F., Shan, S.O. Moustakas, D.T., Alber, F., Egea, P.F., Stroud, R.M., Walter, P., Burlingame,A.L. (2004) Proc. Nat Acad Sci 101, 16454-9
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Structural Basis for Mobility in the 1.1 Å Crystal Structure of the NG Domain of Thermus aquaticus Ffh. Ramirez U.D, Minasov G, Focia P.J, Stroud R.M, Walter P., Kuhn, P., Freymann, D. M. (2002) J Mol Biol 320: 783-99.
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The Signal Recognition Particle.
Keenan, R.J., Freymann, D.M., Stroud, R.M., and Walter, P. (2001).
Ann. Rev. of Biochemistry 70:755-75.
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Signal Sequence Recognition and Protein Targeting.
Stroud, R.M. and Walter, P. (1999).
Current Opinion in Structural Biology 9: 754-759.
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Functional changes in the structure of the SRP GTPase on binding GDP and Mg2+ GDP.
Freyman, DM; Keenan, RJ; Stroud, RM; and Walter, P. (1999)
Nature Structural Biology 6, 793-801.  
PDB Accession Nos. 1NG1, 2NG1 , 3NG1 
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View PDB structure 1NG1, 2NG1, 3NG1
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Crystal structure of the signal sequence binding subunit of the signal recognition particle.
Keenan, RJ; Freymann, DM; Walter, P; Stroud, RM. (1998)
Cell  94, 181-191.  
PDB Accession No. 2FFH
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Structure of the conserved GTPase domain of the signal recognition particle.
Freymann, DM; Keenan, RJ; Stroud, RM; and Walter, P.  (1997)
Nature 385, 361-64  
PDB Accession No. 1FFH
Review abstract
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