Stroud Lab at UCSF : Structure Gallery

Vector Log

Structure Gallery

HIV Protease

PDB Structure Downloads
No. 1KZK
No. 1AZ5
No. 3AID
No. 1YTG, 1YTH, 1YTI, 1YTJ
No. 2SAM
No. 1AID, 2AID

Figure 1: 1.09Å structure of HIV Protease bound to resistance busting inhibitor

Reiling, Craik, and Stroud
Agouron compound in Phase III clinical trials and is effective against multiple drug resistant strains of HIV1.

Figure 2

Unprecedented resolution will lend new insight into catalytic mechanism and substrate binding.